Table 4 Trypanotolerance candidate genes co-localised with regions of reduced heterozygosity (RORH) in Djallonke and Sahelian sheep and the reported orthologs in the cattle genome
Sheep Breed | Genomic region (bp) co-localised with RORH (Oar_v3.1) | Candidate genes | Orthologous loci in Cattle UMD v 3.1 |
|---|---|---|---|
Djallonke | 1:99,623,159-99,650,475 | CTSS | 3:20,024,302-20,047,228 |
Djallonke | 2:165,154,368-165,495,812 | ARHGAP15 | 2:53,065,587-53,732,838 |
Djallonke | 4:79,355,697-79,366,930 | INHBA | 4:79,986,254-79,997,754 |
Both | 7:9,272,393-9,359,760 | SCAMP1 | 10:9,369,310-9,520,700 |
Both | 5:16,922,626-16,924,761 | TICAM1 | 7:20,547,964-20,550,264 |
Djallonke | 8:57,581,762-57,631,158 | STX7 | 9:71,381,757-71,455,585 |
Djallonke | 17:62,105,682-62,115,444 | RAB35 | 17:64,724,244-64,742,928 |
Djallonke | 24:25,905,178-25,915,071 | CD19 | 25:164,039-26,169,956 |