Identification of loci associated with conception rate in primiparous Holstein cows

BMC Genomics

Table 2 Loci associated with cattle fertility across studies

BTA¹	Region (Mb)²	Previous Study(s)³	Previous Phenotype(s)⁴	Previous Breeds⁵	Current Study Phenotype(s)⁶
1	16–17	78	AISC	Holstein^N	CCR1
1	25–26	81	DPR	Holstein^U	CCR1
1	62–30	78	AISC	Holstein^N	CCR1 & TBRD
1	83–84	78	AISH	Holstein^N	CCR1 & TBRD
1	86–87	78	AISC	Holstein^N	CCR1
2	53–54	78	AISC	Holstein^N	CCR1
2	123–124	21,78	HCR1 & TBRD[21]; AISH[78]	Holstein^N,U	CCR1
3	72–73	78	AISC	Holstein^N	CCR1 & TBRD
3	81–82	78	AISC	Holstein^N	TBRD
3	98–99	21	HCR1 & TBRD	Holstein^U	CCR1 & TBRD
4	37–38	21	HCR1 & TBRD	Holstein^U	CCR1 & TBRD
5	21–22	21	TBRD	Holstein^U	CCR1
5	36–37	21	HCR1	Holstein^U	CCR1 & TBRD
6	38–39	37	P28	Angus crosses^U	CCR1 & TBRD
6	93–94	21,78	HCR1 & TBRD[21]; AISC[78]	Holstein^N,U	CCR1
8	20–21	78	AISC	Holstein^N	CCR1 & TBRD
8	24–25	78	AISC & AISH	Holstein^N	CCR1
9	87–88	78	AISC	Holstein^N	CCR1
11	16–17	21	HCR1 & TBRD	Holstein^U	CCR1 & TBRD
11	77–78	78	AISH	Holstein^N	CCR1 & TBRD
11	86–87	21	HCR1 & TBRD	Holstein^U	CCR1
13	29–30	78,79	AISH[78]; ICF[79]	Holstein^C,N	CCR1
15	26–27	21	HCR1 & TBRD	Holstein^U	CCR1 & TBRD
17	3–4	78, 80	FTI, IFLC[78]; CI[80]	Holstein^A,I,N, Jersey^A	CCR1
17	74–75	21	HCR1 & TBRD	Holstein^U	CCR1
17	75–76	21	HCR1 & TBRD	Holstein^U	CCR1 & TBRD
18	8–9	78	AISC	Holstein^N	TBRD
18	21–22	21	HCR1 & TBRD	Holstein^U	CCR1
19	7–8	21	HCR1 & TBRD	Holstein^U	CCR1
20	27–28	21,78	TBRD[21]; AISC[78]	Holstein^N,U	CCR1 & TBRD
24	25–76	78	AISC	Holstein^N	CCR1
26	19–20	78	AISC	Holstein^N	CCR1
26	28–29	21,78	HCR1 & TBRD[21]; AISC[78]	Holstein^N,U	CCR1
26	40–41	81	DPR	Holstein^U	CCR1
27	21–22	21	HCR1 & TBRD	Holstein^U	CCR1 & TBRD
28	29–30	78, 80	NRRH[78]; CI[80]	Holstein^A,I,N, Jersey^A	CCR1

¹Bos taurus chromosome (BTA) location of the locus
²Region associated locus is located in (in Mb) as measured by numbered nucleotides in reference to the UMD 3.1 genome assembly (http://bovinegenome.org/?q=node/61; accessed 15 September 2016)
³The citation number for each study a locus was previously associed in is listed
⁴Traits previously associated with loci abbreviated as follows: AISC - number of inseminations to conception in cows; AISC - number of inseminations to conception in heifers; CI - calving interval; HCR1 - conception rate to first insemination in heifers; DFS - days to first service; DPR - daughter pregnancy rate; FTI - fertility index; HCR - heifer conception rate; ICF - interval (in days) from calving to first insemination; IFLC - days from first to last insemination in cows; NRRC - 56 day non return rate in cows; NRRH - 56 day non return rate in heifers; P28- pregnancy success at day 28 post embryo transfer; P42 - pregnancy success within first 42 days of mating; TBRD - number of times bred to conception. If multiple traits are listed from different studies the citation number for study is listed in superscript brackets
⁵Cattle breeds loci were previously identified are listed with the country or region the population was from indicated in superscript as follows: Australia - A; Canada - C; Ireland - I; Nordic - N; United States - U
⁶Phenotype of the current study the loci was associated with: conception rate at first AI service - CCR1 and TBRD

ISSN: 1471-2164