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Table 2 Genes and corresponding conserved domains linked to integrative, conjugative and resistance elements found in contigs 5, 7 and 9 from the draft assembly of strain GP. Families and E-values in bold indicate the best hits obtained with CONJscan [146]. n.a., not applicable

From: Comparative genomics reveals a novel genetic organization of the sad cluster in the sulfonamide-degrader ‘Candidatus Leucobacter sulfamidivorax’ strain GP

SystemContigLocus tagDescriptionFamilyAccessionE-value
 Replication, stabilization and partitioning5D3X82_17420Toxin protein from a toxin/antitoxin systemZeta_toxinpfam064141.6e-19
5D3X82_17550Plasmid partition protein ABcsQ
partition_RepA
COG1192
TIGR03453
2.2e-43
5.7e-16
5D3X82_17555Single-stranded DNA-binding proteinSSB_OBFcd044968.5e-12
7D3X82_18090Plasmid replication proteinRepA_Cpfam047969.0e-07
 Mobilization and conjugative elements5D3X82_17410Plasmid mobilization relaxosome protein MobCMobCpfam057135.7e-05
5D3X82_17470Conjugal transfer proteinTrwC
MOBF
pfam08751
n.a.
9.0e-97
1.3e-85
5D3X82_17385Type IV secretion protein (T4SS)VirB4n.a.1.40e-25
5D3X82_17390Coupling protein (T4CP)VirD4
T4CP2
COG3505
n.a.
4.2e-16
5.7e-40
5D3X82_17405RelaxaseRelaxase
MOBP1
pfam03432
n.a.
9.8e-10
4.20e-40
7D3X82_18105Conjugal transfer proteinTrwC
MOBF
pfam08751
n.a.
3.7e-28
5.3e-105
9D3X82_18250Conjugal transfer proteinTrwC
MOBF
pfam08751
n.a.
7.6e-25
4.1e-106
 Multi-drug and heavy metal resistance5D3X82_17365 D3X82_17695Sulfonamide monooxygenase SadANcnH
CaiA
Acyl-CoA_dh_2
cd01159
COG1960
pfam08028
1.52e-84
1.93e-30
5.8e-20
5D3X82_17485Tet(A)/Tet(B)/Tet(C) family tetracycline efflux MFS transporterMFS_TetAcd173882.4e-145
5D3X82_17505ANT(3″)-Ia family aminoglycoside nucleotidyltransferase AadA1PRK13746
DUF4111
PRK13746
pfam13427
0e+ 00
1.31e-41
5D3X82_17510Quaternary ammonium compound efflux SMR transporter QacE delta 1Multi_Drug_Respfam008931.75e-28
5D3X82_17515Sulfonamide-resistant dihydropteroate synthase Sul1Pterin_bindpfam008091.8e-87
5D3X82_17685Mercury(II) reductaseMerATIGR020531.2e-171