Table 3 Resistance genes among the patient and environmental isolates
Isolates | 1566D | 2035D | 2036D | 2037D | 2038D | 2039D | 2040D |
|---|---|---|---|---|---|---|---|
MLST | ST11 | ST11 | ST2632 | ST11 | ST11 | ST11 | ST11 |
pMLST | IncF[F33:A-:B-] | IncF[F33:A-:B-] | IncHI1, IncF | IncF[F33:A-:B-] | IncF[F33:A-:B-] | IncF[F33:A-:B-] | IncF[F33:A-:B-] |
Plasmids | IncR, ColRNAI | IncR, ColRNAI | IncR, ColRNAI | IncR, ColRNAI | IncR, ColRNAI | IncR, ColRNAI | IncR, ColRNAI |
Penicillins: Ampicillin/ Narrow-Spectrum Cephalosporins: cefazolin and cefotetan | blaCTX-M-14 blaKPC-2 blaLEN12 blaTEM-1B | blaCTX-M-65 blaKPC-2 blaSHV-11 blaTEM-1B | blaCTX-M-3 blaSHV-93 | blaCTX-M-65 blaKPC-2 blaSHV-11 blaTEM-1B | blaCTX-M-65 blaKPC-2 blaSHV-11 blaTEM-1B | blaCTX-M-65 blaKPC-2 blaSHV-11 blaTEM-1B | blaCTX-M-14 blaKPC-2 blaSHV-11 blaTEM-1B |
β-lactam inhibitors/ Carbapenems | blaKPC-2 | blaKPC-2 | – | blaKPC-2 | blaKPC-2 | blaKPC-2 | blaKPC-2 |
Extended-Spectrum Cephalosporins/ Monobactam | blaCTX-M-14 | blaCTX-M-65 | blaCTX-M-3 | blaCTX-M-65 | blaCTX-M-65 | blaCTX-M-65 | blaCTX-M-65 |
Aminoglycosides | rmtB | rmtB | aac(3)-IId | rmtB | aac(3)-IId rmtB | aac(3)-IId rmtB | aac(3)-IId rmtB |
Fluoroquinolones | QnrS1 | – | oqxA oqxB | – | QnrS1 | QnrS1 | QnrS1 |
Phosphonic Acid | fosA | fosA | fosA | fosA | fosA | fosA | fosA |
Phenicol | – | catA2 | catA1 | catA2 | catA2 | catA2 | catA2 |
Folate-pathway Inhibitors | dfrA1 | – | dfrA17 | – | dfrA1 | dfrA1 | dfrA1 |