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Table 4 Summary of QTL detected by GEMMA for YW in U.S. Gelbvieh beef cattle

From: Genome-wide association and genotype by environment interactions for growth traits in U.S. Gelbvieh cattle

Chr_MbMAF-log10 P-valueSupporting SNPsPositional Candidate GenesLead SNP LocationScientific Precedence [reference]; organism; trait
6_39a0.30520.81103LCORLIntron[18, 21, 30, 37,38,39, 55, 56]; Cattle, sheep; stature, SimAngus mid-test metabolic weight association, muscle and organ growth, feed intake and gain association, growth and carcass traits, skeletal growth and muscle mass
14_25a0.39913.823PLAG13’UTR[2, 14, 18, 21, 30, 32,33,34]; Cattle; SimAngus mid-test metabolic weight association, carcass weight, stature, body weight and milk
6_38a0.22211.0020HERC6, PPM1KIntergenic[49, 58, 59]; Cattle; milk, fat, and protein yield, metabolic processes, feed efficiency association
6_42a0.34411.0011KCNIP4Intron[39, 41, 42]; Chicken, cattle, human; growth and muscle mass trait association, potassium channel activity
6_37a0.33010.128SNCA, GPRIN3Intergenic[61,62,63,64]; Human, goat, equine; neurological regulation, milk and meat associations, tendon tissue association
5_60a0.0429.622LOC527216, LOC788998IntergenicNA
6_41a0.2478.446SLIT2Intron[39, 49,50,51,52,53]; Cattle, chicken, human; milk fat and protein association, organ and muscle weight, development of central nervous system, tumor suppressor activity
6_36a0.2278.2320CCSER1Intron[14, 60]; Cattle, human; body and carcass weight association, regulator of mitosis
14_26a0.3576.9412IMPAD1, FAM110BIntergenic[30, 32, 34, 40]; Cattle; SimAngus mid-test metabolic weight association, carcass weight association, stature and body weight association, bone and cartilage system
7_93a0.2866.2314LOC101905238,
ARRDC3
Intergenic[14, 22, 30, 46]; Cattle; body and carcass weight association, calving ease, average daily gain in Hereford, growth and muscularity, birth weight, weaning weight, yearling weight, and ribeye area in Angus
6_40a0.1096.2111LOC782905, SLIT2Intergenic[39, 49,50,51,52,53]; Cattle, chicken, human; milk fat and protein association, organ and muscle weight, development of central nervous system, tumor suppressor activity
14_27a0.3486.046NSMAFIntron[30, 68]; Cattle, human; Angus residual feed intake association, immune system response
2_050.4975.153IWS1Intron[69]; Human; chromatin modification, histone chaperone, maintenance of virus latency
  1. a Indicates QTL was detected in EMMAX analysis