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Table 2 Differentially expressed genes on the pathways of energy metabolism and ureagenesis in the goat liver

From: Transcriptomic analyses suggest a dominant role of insulin in the coordinated control of energy metabolism and ureagenesis in goat liver

Item

Gene Description

EC

LNFCa

MNFCa

Energy metabolism

fatty acid synthase

2.3.1.85

1.65 ± 0.11

14.87 ± 0.17

HMGCS1

2.3.3.10

15.02 ± 0.28

101.41 ± 6.06

ACSS2

6.2.1.1

6.92 ± 0.43

31.98 ± 0.72

acetyl-CoA carboxylase alpha

6.4.1.2

1.77 ± 0.09

6.50 ± 0.12

ATP citrate lyase

2.3.3.8

2.88 ± 0.22

7.19 ± 0.37

acetyl-CoA carboxylase beta

6.4.1.2

3.59 ± 0.25

8.29 ± 0.22

enolase family member 4

4.2.1.11

1.35 ± 0.18

2.94 ± 0.12

AKR1B1

1.1.1.21

2.46 ± 0.17

5.21 ± 0.82

ALDH7A1

1.2.1.3

42.70 ± 0.63

89.68 ± 2.81

citrate synthase

2.3.3.1

4.01 ± 0.09

8.07 ± 0.15

acyl-CoA dehydrogenase

1.3.8.9

353.15 ± 15.80

176.21 ± 4.05

acetyl-CoA acetyltransferase 1

2.3.1.9

377.39 ± 13.05

187.99 ± 7.42

acyl-CoA oxidase 1

1.3.3.6

94.65 ± 2.52

46.41 ± 0.49

acyl-CoA synthetase

6.2.1.3

67.04 ± 1.77

32.23 ± 0.64

enoyl-CoA hydratase

1.1.1.211

83.85 ± 0.67

39.79 ± 0.47

malonyl-CoA decarboxylase

4.1.1.9

61.83 ± 3.32

28.86 ± 1.55

fructose-bisphosphatase 2

3.1.3.11

3.63 ± 0.17

1.69 ± 0.32

carnitine palmitoyltransferase 2

CPT2

39.61 ± 2.37

17.92 ± 0.56

aldolase, fructose-bisphosphate B

4.1.2.13

4266.95 ± 240.93

1924.19 ± 82.61

carnitine palmitoyltransferase 1B

CPT1

2.91 ± 0.24

1.29 ± 0.09

ACSM1

6.2.1.2

801.14 ± 21.60

343.51 ± 10.80

acetyl-CoA acyltransferase 1

2.3.1.16

1292.50 ± 70.23

467.31 ± 11.32

carnitine palmitoyltransferase 1A

CPT1

44.81 ± 2.06

14.18 ± 0.31

lactate dehydrogenase B

1.1.1.27

343.71 ± 35.60

107.23 ± 8.80

acyl-CoA thioesterase 12

3.1.2.1

3.68 ± 0.31

1.13 ± 0.08

glucose-6-phosphatase

3.1.3.9

187.53 ± 1.98

55.81 ± 0.83

pyruvate carboxylase

6.4.1.1

312.03 ± 11.05

91.19 ± 1.30

fructose-bisphosphatase 1

3.1.3.11

1307.74 ± 57.02

312.13 ± 12.39

HMGCS2

2.3.3.10

841.12 ± 26.52

131.76 ± 4.35

Ureagenesis

pyrroline-5-carboxylate reductase 1

1.5.1.2

5.27 ± 0.90

50.95 ± 1.83

glutamate dehydrogenase 1

1.4.1.3

377.55 ± 10.60

766.01 ± 25.12

glutamate-ammonia ligase

6.3.1.2

92.93 ± 0.93

185.03 ± 9.79

argininosuccinate lyase

4.3.2.1

654.00 ± 24.75

326.93 ± 9.07

carbamoyl-phosphate synthase 1

6.3.4.16

519.96 ± 3.93

257.68 ± 5.98

argininosuccinate synthase 1

6.3.4.5

2293.04 ± 88.68

1134.59 ± 28.93

glutamic-oxaloacetic transaminase 1

2.6.1.1

89.37 ± 3.70

44.02 ± 0.50

arginase 2

3.5.3.1

1.71 ± 0.32

0.77 ± 0.28

arginase 1

3.5.3.1

853.86 ± 49.01

375.18 ± 32.10

glutaminase 2

3.5.1.2

79.93 ± 2.13

35.07 ± 1.18

histidine ammonia-lyase

4.3.1.3

47.15 ± 0.38

18.18 ± 1.16

  1. HMGCS1:3-hydroxy-3-methylglutaryl-CoA synthase 1; ACSS2: acyl-CoA synthetase short-chain family member 2; AKR1B1: aldo-keto reductase family 1 member B; ALDH7A1: aldehyde dehydrogenase 7 family member A1; ACSM1: acyl-CoA synthetase medium-chain family member 1; HMGCS2: 3-hydroxy-3-methylglutaryl-CoA synthase 2. a values are mean value ± standard error
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BMC Genomics

ISSN: 1471-2164

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