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Table 2 COG functional classification of genes at the unique node connections of the six main clades

From: Modification of the genome topology network and its application to the comparison of group B Streptococcus genomes

Function classification

clade A

clade B

clade C

clade D

clade E

clade F

total

[S] Function unknown

159

141

44

44

52

14

454

[R] General function prediction only

127

123

35

38

30

9

362

[G] Carbohydrate transport and metabolism

73

108

25

22

38

3

269

[L] Replication, recombination and repair

68

58

29

44

32

26

257

[J] Translation, ribosomal structure and biogenesis

82

58

16

28

18

6

208

[M] Cell wall/membrane/envelope biogenesis

58

62

34

32

12

6

204

[K] Transcription

65

54

22

33

19

5

198

[E] Amino acid transport and metabolism

66

70

13

16

16

5

186

[H] Coenzyme transport and metabolism

42

62

16

22

14

6

162

[P] Inorganic ion transport and metabolism

45

54

23

18

10

3

153

[F] Nucleotide transport and metabolism

53

46

9

4

12

3

127

[O] Posttranslational modification, protein turnover, chaperones

24

33

10

4

12

3

86

[U] Intracellular trafficking, secretion, and vesicular transport

20

33

14

4

4

3

78

[V] Defense mechanisms

26

20

5

10

9

5

75

[D] Cell cycle control, cell division, chromosome partitioning

14

21

17

8

4

4

68

[T] Signal transduction mechanisms

21

20

5

4

10

2

62

[C] Energy production and conversion

18

17

3

2

4

1

45

[I] Lipid transport and metabolism

14

18

5

2

2

0

41

[Q] Secondary metabolites biosynthesis, transport and catabolism

6

8

0

0

0

0

14

[N] Cell motility

0

3

2

0

0

0

5

total

981

1009

327

335

298

104