Fig. 2

Phylogeny-wide change in sequence-specific TF families with < 50 members. The presence of orthologous TF genes across the Ddis, Dpur, Dlac, Ppal and Dfas genomes is indicated by green squares below species names, which are shown in a lighter tone or with a black border, when compared to the majority, the functional domains or the developmental regulation, respectively, are not conserved. Where the number of non-conserved features is larger than 3, all differ from each other. The colour coding of the 6th, 7th and 8th square in each row respectively represent the developmental expression profile in the majority of species, the prestalk/prespore specificity when conserved between Ddis and Dpur slugs, the spore or stalk specificity when conserved between species, the cup and vegetative cell specificity in Ddis. The 9th square represents up- or down regulation in encystation of Ppal. Cup cells are only present in group 4 and are bordered red or blue when the orthologs in group 2 or 3 show spore- or stalk-specific expression, respectively. Grey reflects lack of specificity or conflicting data between species or replicate experiments and white reflects absence of data. The genes are listed by the Ddis gene names or 12 digit Dictybase gene identifiers from which the DDB_G0 prefix was omitted. The names of genes with known biological roles in Ddis are bordered in red. The gene identifiers and locus tags for the Dpur, Dlac, Ppal and Dfas genes are listed in Additional file 1: Table S2 together with all data on which this figure and Fig. 3 and Additional file 1: Figure S18 are based