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Fig. 7 | BMC Genomics

Fig. 7

From: Investigation of the host transcriptional response to intracellular bacterial infection using Dictyostelium discoideum as a host model

Fig. 7

Identified orthologues and their regulation in response to infection of D. discoideum and human macrophages. a Number of differentially regulated D. discoideum genes identified as orthologues to human genes. b Number of regulated human genes orthologous to genes in D. discoideum (denoted as capital letters corresponding to letters in the Venn diagram in a) in response to L. pneumophila (Lp) [20] or M. tuberculosis (Mtb) [19]. In the comparison with both Lp and Mtb (Lp/Mtb), similar regulation refers to the similar differential expression in response to either Mtb, Lp or both. Full list of identified orthologues and their regulation in D. discoideum and macrophages is available in Additional file 7

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