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Table 5 The ratios of essential genes to the seed nodes selected in the proposed local network alignment (after preprocessing), the ratio of essential genes to the genes interconnected between networks (before preprocessing), and the ratio of essential genes to randomly selected nodes in a PPI network

From: LePrimAlign: local entropy-based alignment of PPI networks to predict conserved modules

essential gene

seed nodes selected

interconnected nodes

random nodes in a network

data set

after preprocessing

before preprocessing

 

DEG data set

0.586

0.445

0.305

MIPS data set

0.566

0.420

0.278

  1. The sets of essential genes were obtained from DEG and MIPS