BMC Genomics

Table 1 Results for individual tools

From: Improving CRISPR guide design with consensus approaches

	Wang				Doench
Tool name n	Accepted	Precision	Recall	NPV	Accepted	Precision	Recall	NPV
Cas-Designer	206	0.612	0.172	0.372	668	0.210	0.377	0.803
SSC	632	0.851*	0.736	0.641	1056	0.277	0.787	0.899
PhytoCRISP-Ex	348	0.764	0.364	0.434	524	0.235	0.332	0.812
TUSCAN	737	0.715	0.721	0.528	1390	0.245*	0.919	0.934
sgRNAScorer2	484	0.833	0.551	0.521	893	0.270	0.650	0.863
mm10db	330	0.652	0.294	0.385	384	0.227	0.235	0.805
CHOPCHOP	273	0.843	0.315	0.441	537	0.294	0.426	0.837
CHOPCHOP-Xu	638	0.853*	0.744	0.648	1061	0.197	0.563	0.792
CHOPCHOP-MM	338	0.716	0.331	0.412	761	0.191	0.391	0.791
WU-CRISPR	286	0.818	0.320	0.437	366	0.511*	0.504	0.875
FlashFry	141	0.844	0.163	0.405	210	0.586*	0.332	0.848

^*indicates tool was trained using this dataset

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ISSN: 1471-2164

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