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Table 1 Results for individual tools

From: Improving CRISPR guide design with consensus approaches

  Wang   Doench
Tool name n Accepted Precision Recall NPV Accepted Precision Recall NPV
Cas-Designer 206 0.612 0.172 0.372 668 0.210 0.377 0.803
SSC 632 0.851* 0.736 0.641 1056 0.277 0.787 0.899
PhytoCRISP-Ex 348 0.764 0.364 0.434 524 0.235 0.332 0.812
TUSCAN 737 0.715 0.721 0.528 1390 0.245* 0.919 0.934
sgRNAScorer2 484 0.833 0.551 0.521 893 0.270 0.650 0.863
mm10db 330 0.652 0.294 0.385 384 0.227 0.235 0.805
CHOPCHOP 273 0.843 0.315 0.441 537 0.294 0.426 0.837
CHOPCHOP-Xu 638 0.853* 0.744 0.648 1061 0.197 0.563 0.792
CHOPCHOP-MM 338 0.716 0.331 0.412 761 0.191 0.391 0.791
WU-CRISPR 286 0.818 0.320 0.437 366 0.511* 0.504 0.875
FlashFry 141 0.844 0.163 0.405 210 0.586* 0.332 0.848
  1. *indicates tool was trained using this dataset