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Table 5 Consensus between machine-learning methods, removing models trained on the associated test dataset

From: Improving CRISPR guide design with consensus approaches

  Wang Doench
Consensus level n Accepted Precision Recall NPV Accepted Precision Recall NPV
1 927 0.695 0.881 0.641 1655 0.216 0.965 0.930
2 624 0.793 0.677 0.567 1242 0.241 0.806 0.880
3 295 0.881 0.356 0.461 653 0.254 0.447 0.827
4 120 0.892 0.146 0.405 221 0.290 0.173 0.811
5 20 0.950 0.026 0.380 - - - -
  1. Tools considered for Wang: sgRNAScorer2, CHOPCHOP-MM, WU-CRISPR, FlashFry and TUSCAN. Tools considered for Doench: sgRNAScorer2, SSC, CHOPCHOP-MM and CHOPCHOP-Xu