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Table 6 Consensus when optimising for both datasets (excluding models trained on test data, excluding poor performing tools, no more than five tools, recall approx. 20%)

From: Improving CRISPR guide design with consensus approaches

 

Wang

 

Doench

Consensus level n

Accepted

Precision

Recall

NPV

Accepted

Precision

Recall

NPV

1

811

0.724

0.803

0.598

1327

0.229

0.819

0.870

2

453

0.817

0.506

0.496

762

0.280

0.574

0.854

3

148

0.912

0.185

0.416

225

0.356

0.216

0.820

4

23

0.957

0.030

0.381

24

0.500

0.032

0.802

  1. Tools considered here: sgRNAScorer2, CHOPCHOP, PhytoCRISP-Ex, mm10db
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BMC Genomics

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