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Fig. 8 | BMC Genomics

Fig. 8

From: A generative model for constructing nucleic acid sequences binding to a protein

Fig. 8

The alignment of the generated DNA sequences to the known NFATC1-binding aptamer [24] (top) and NFKB1-binding aptamer [25] (bottom). Top 100 sequences with high binding specificity scores were selected for the alignment. The cumulative binding specificity score of the aligned sequences is shown in the line chart and heatmap. In the heatmap, a position with a high accumulated binding specificity is shown in yellow and that with a low binding specificity is shown in navy

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