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Table 5 Top 5 common and unique REVIGO GO annotation subsets of Hyper-Variable and Hypo-Variable essential genes in breast, cerebellum, and frontal cortex tissues

From: Human gene expression variability and its dependence on methylation and aging

 

Breast-Specific Probe-Mapped Genes

Cerebellum-Specific Probe-Mapped Genes

Frontal Cortex-Specific Probe-Mapped Genes

Hyper-Variable Essential Genes

Chordate embryonic development

Regulation of cell development

Positive regulation of cell differentiation

Cellular response to growth factor stimulus

Epithelial cell migration

Transmembrane receptor protein tyrosine kinase signalling pathway

Mesenchymal cell apoptotic process

Positive regulation of cell proliferation

Epithelial cell migration

Carboxylic acid biosynthesis

Cellular response to growth factor stimulus

Regulation of actin cytoskeleton organization

Cell-substrate junction assembly

Anterograde trans-synaptic signalling

Regulation of lipase activity

Hypo-Variable Essential Genes

DNA repair

DNA repair

DNA repair

Regulation of cellular protein localization

Protein oligomerization

Peptide transport

Mitochondrial genome maintenance

Positive regulation of viral process

Regulation of type I interferon production

Chordate embryonic development

Negative regulation of cell cycle

Response to UV

Protein modification by small protein removal

Lysosomal transport

Phosphorylation