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Table 6 Pearson’s Chi-Squared Test Standardized Residuals. We tested the independence between the methylation state clusters and the EV classifications in cerebellum and frontal cortex tissues and found a significant relationship between the two variables (p = 7.57 × 10–36 and p = 1.58 × 10–59, respectively)

From: Human gene expression variability and its dependence on methylation and aging

 

Cerebellum Tissue

Frontal Cortex Tissue

Non-Methylated

Medium Methylated

Highly Methylated

Non-Methylated

Medium Methylated

Highly Methylated

Hypo-Variable

11.98

− 5.69

−9.04

14.84

− 7.11

−10.79

Non-Variable

−7.52

0.06

8.59

−10.00

−0.04

11.73

Hyper-Variable

0.07

4.21

−3.58

−0.23

6.23

−5.47