Table 4 Distribution of the single nucleotide polymorphisms (SNPs) at the open reading frame (ORF) of the prion protein gene (PRNP) in various species

Human

G54S, P68P, G114 V, G127 V, M129 V, G142S, R148H, N171S, D178N, V180I, T183A, T188K, E200K, V203I, R208H, V210I, E211Q, E219K, M232R, P238S

[6, 31, 32]

Sheep

S98R, Q101R, M112 T, A116P, A116E, G127S, A136V, A136T, M137 T, S138R, L141F, I142K, H143R, G145 V, N146S, D147E, Y152F, R154H, P168L, Q171R, Q171H, Q171K, Y172D S173 N, Q175R, N176K, V179E, N184H, Q189L, R231R, L237 L

[33,34,35,36]

Goats

W18R, V21A, L23P, G37 V, P42P, G49S, Q101R, Q101Q, W102G, K107K, T110P, V125 V, G127S, L133Q, M137I, S138S, I142M, I142T, I42I, H143R, N146D, N146S, R151H, R154H, P168Q, V179 V, D181D, T194P, F201F, T202 T, K207K, R211Q, R211G, I218L, T219 L, Q220H, Q222K, Q222Q, G232 W, G232G, S240P

[37, 38]

Cattle

K3T, S8S, V21E, S46I, N50S, P54S, G58G, G66G, G67S, W68R, G73A, Q78Q, G83G, K117K, M145 V, S146 N, S154S, S154 N, Y156C, Y174C, N184D, N185 N, N192 N, V200F, V200A, T204A, K205E, F209S, T210 T, T212A, K215R, M216 T, Q223H, I244V, L245F, P249P, I252F, L253P

[22,23,24,25]

Horse

N175K

[5]

Chickens

ND^a

[30], This study