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Fig. 3 | BMC Genomics

Fig. 3

From: Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation

Fig. 3

Commitment and development are distinctly regulated processes. a The genes increased in expression during commitment [18, 20, 25] were compared to transcripts increased in abundance during gametocytogenesis (Clusters 6–10, 2425 transcripts) with overlapping genes of interest: ap2-g (pf3d7_1222600), sap18 (pf3d7_0711400), sir2a (pf3d7_1328800), lsd2 (pf3d7_ 0801900), lsd1 (pf3d7_ 1,211,600), set3 (pf3d7_ 0827800) and genes only increased during commitment hp1 (pf3d7_1220900), hda2 (pf3d7_1008000), gdv1 (pf3d7_0935400), iswi (pf3d7_0624600), sn2fl (pf3d7_1104200) highlighted in heatmaps. b The increased and developmentally regulated gene clusters also contained significantly enriched regulatory 5′ and 3′ UTR motifs identified using the FIRE algorithm [54]

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