Fig. 5
From: miR-380-3p regulates melanogenesis by targeting SOX6 in melanocytes from alpacas (Vicugna pacos)
Effect of miR-380-3p on melanin production in alpaca melanocytes. a Effect of miR-380-3p overexpression and knockdown on melanogenesis compared with negative control (NC) conditions. b Effect of miR-380-3p on cell pellets. c Effect of miR-380-3p overexpression and SOX6 on melanogenesis compared with negative control (NC) conditions. d Effect of miR-380-3p overexpression and SOX6 siRNA on melanogenesis compared with negative control (NC) conditions. e Effect of miR-380-3p overexpression and inhibition in melanocytes on melanin according to Fontana-Masson staining. f Quantitative analysis of the distribution of melanin particles. The bars represent the mean ± standard error (n = 3). ***P < 0.001