Fig. 3

Overall transcriptome profiles of all DEGs. a Heatmap of all DEGs. Green and red indicate the low and high expression levels, respectively. C1, C2 and C3 indicate the control group, F1, F2 and F3 indicate the fasting group, and R1, R2 and R3 indicate the refeeding group. Cluster1 contains genes significantly down regulated in fasting group compared to control, with the exception of genes also significantly changed in refeeding group compared to control; Cluster2 contains genes significantly down regulated in fasting group compared to refeeding group, with the exception of genes also significantly changed in refeeding group compared to control; Cluster3 contains genes significantly up regulated in refeeding group compared to control; Cluster4 contains genes significantly down regulated in refeeding group compared to control; Cluster5 contains genes significantly up regulated in fasting group compared to control, with the exception of genes also significantly changed in refeeding group compared to control; Cluster6 contains genes significantly up regulated in fasting group compared to refeeding group, with the exception of genes significantly changed in refeeding group compared to control. The full list of these DEGs can be found in Additional file 2: Table S2. b UpSet chart showing intersection between different DEG sets from various comparisons. The vertical bar plot reports the intersection size, the dot plot reports the set participation in the intersection, and the horizontal bar plot reports the set sizes