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Fig. 5 | BMC Genomics

Fig. 5

From: Stratified reconstruction of ancestral Escherichia coli diversification

Fig. 5

Patterns of distribution by functional categories of gained/lost gene based on Cluster Orthologous Genes (COG) classification. Four main categories were analyzed: Panel a) Cell interactions, including the functional categories M (cell wall/membrane/ envelope biogenesis), N (cell motility), U (intracellular trafficking/ secretion/ transport), V (defense mechanism) and W (extracellular structure). Panel b) Replication, including D (cell division), J (replication, ribosomal and biogenesis), K (transcription), L (replication, recombination and repair), O (post-translational modification, chaperones), T (signal transduction). Panel c) Metabolism, including C (energy production), E (amino acid transport), F (nucleotide transport), G (coenzyme transport); I (lipid transport), P (inorganic ion transport), Q (secondary metabolites). Panel d) Other functions, including S (unknown), R (general functions) and X (mobilome, prophage). Panel e) Overall representation, including all gains and losses of genes in these categories. Orange corresponds to gained genes and blue to lost genes. Phylogroup D was used as reference genome because the number of available sequences in the previously used outgroups was very low

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