Fig. 1From: Network analysis uncovers putative genes affecting resistance to tick infestation in Braford cattle skinFunctional enrichment of differentially expressed genes (DEGs) in Braford skin according to host phenotype and tick infestation. Venn diagrams show the distribution of DEGs from inter- (Rpre vs. Spre (1) and Rpost vs. Spost (2)) and intragroup (Rpost vs. Rpre (3) and Spost vs. Spre (4)) comparisons: (a) all DEGs, (b) only the annotated ones, or (c) only annotated TopDEGs. Functional annotation based on protein classes of DEGs from (d) inter- and (e) intragroup comparisons are shown, represented by a symbol following the Metacore® reference guide (https://portal.genego.com/legends/MetaCoreQuickReferenceGuide.pdf). Actual: number of network objects from the dataset(s) for a given protein class; n: number of network objects in the dataset(s); R: number of network objects of a given protein class in the complete database or background list; N: total number of network objects in the complete database or background list; Expected: mean value for hypergeometric distribution (n*R/N); p-value: probability to have the given value of Actual or higher (or lower for negative z-score); z-score: ((Actual-Expected)/sqrt(variance)); Ratio: connectivity ratio (Actual/Expected); % in Dataset: fraction of network objects with a selected function in the datasetBack to article page