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Fig. 10 | BMC Genomics

Fig. 10

From: Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in mouse lung

Fig. 10

Genes that are differentially regulated in the nodal pathway related to IL-6. The following genes were among the up-regulated ones in the WT PA group compared to the rest Cdkn2d, Cdkn1a, Mcl1, Stat3, Cish and Fosl2. Notably, Cish represents CIS family members which are known to be cytokine-inducible negative regulators of cytokine signaling. The down regulated genes include Stat1, Cdkn2c and Irs1

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