Fig. 5From: Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in mouse lungGenes differentially regulated in the nodal pathway related to PKC δ (cluster 8). This heatmap cluster combines data from related pathways shown in Additional file 3: Table S2. Among the genes prominently up-regulated by PA in the WT include Sele, Pip5k1a, Lcp2, Nr4a1, Selp and Nos2. The genes down-regulated include Gng7, Mef2c, Gna11, Prkcz, Rasgrp2, Ppp1r14a, Prkg2, Gnb4 and PrkacaBack to article page