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Fig. 2 | BMC Genomics

Fig. 2

From: Hypothesis: protein and RNA attributes are continuously optimized over time

Fig. 2

Turnover-dependent decrease in peptide variance. a Variance of all HeLa peptides used to compute individual protein-specific turnover values. b Median of normalized peptide variance (Variance/(median turnover ratio)2) plotted in bins of proteins sorted according to their median turnover derived from all measured peptides. c Peptide variance of all proteins that were measured with exactly 15 peptides. d Measured peptide values for three proteins indicated with arrows in (c). Scavenger mRNA-decapping enzyme DcpS (), Tight junction protein ZO-1 (), Ferritin heavy chain () (e) Normalization of (d) by division through the median protein turnover value of the respective protein

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