Fig. 6

Visualization of connections of genes in various modules by heatmap and Cytoscape 3.3.0. In the top part of the A-F picture, heatmap plots depicting the relationships among the 30 most significant genes identified by network screening. Each column and row of the heat map corresponds to a single gene; light colors mean topological overlaps; progressively darker colors correspond to higher topological overlaps. In the lower part of the A-F picture, connections of 30 hub genes which were selected from top 150 highly connected genes and the top 300 connections of highly connected genes of higher correlation modules. Plots A-F depicts the hub gene network of L3 h, L12 h, L48 h, R3h, R12h and R48h, respectively