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Table 2 Number of differentially expressed gene (DEG) determined from comparison of treated groups relative to their respective PBS-treated group. Treatments were the bacterial mimic peptidoglycan (PGN) and viral mimic Poly I:C. An arrow refers to up or down expression of DEG. A value in parenthesis is an average value of DEGs

From: Effect of growth rate on transcriptomic responses to immune stimulation in wild-type, domesticated, and GH-transgenic coho salmon

Tissue Comparison D TR TF W
Head kidney PGN-treated vs. PBS-treated 3 ↑ 3 (6.6) 71 ↑ 64 (11.0) 6 ↑ 5 (17.3) 29 ↑ 28 (9.7)
↓ 7 (−3.8) ↓ 1 (−5.9) ↓ 1 (−5.5)
  Poly I:C-treated vs. PBS-treated 0 97 ↑ 97 (6.6) 0 7 ↑ 7 (7.1)
Liver PGN-treated vs. PBS-treated 14 ↑ 14 (18.6) 123 ↑ 109 (11.0) 32 ↑ 27 (14.4) 80 ↑ 72 (9.8)
  ↓ 14 (−6.7) ↓ 5 (−4.8) ↓ 8 (−11.8)
  Poly I:C-treated vs. PBS-treated 1 ↑ 1 (7.3) 25 ↑ 24 (9.8) 0 36 ↑ 36 (7.6)
  ↓ 1 (−3.8)
  1. PBS phosphate-buffered saline, PGN peptidoglycan, Poly I:C polyinosinic-polycytidylic acid. W, non-transgenic (wild-type) coho salmon on a full satiation ration, TF GH transgenic coho salmon on a full satiation ration, TR GH transgenic coho salmon on restricted ration equal to that consumed by W, D domesticated coho salmon on a full satiation ration