Skip to main content

Table 2 Number of differentially expressed gene (DEG) determined from comparison of treated groups relative to their respective PBS-treated group. Treatments were the bacterial mimic peptidoglycan (PGN) and viral mimic Poly I:C. An arrow refers to up or down expression of DEG. A value in parenthesis is an average value of DEGs

From: Effect of growth rate on transcriptomic responses to immune stimulation in wild-type, domesticated, and GH-transgenic coho salmon

Tissue

Comparison

D

TR

TF

W

Head kidney

PGN-treated vs. PBS-treated

3

↑ 3 (6.6)

71

↑ 64 (11.0)

6

↑ 5 (17.3)

29

↑ 28 (9.7)

–

↓ 7 (−3.8)

↓ 1 (−5.9)

↓ 1 (−5.5)

 

Poly I:C-treated vs. PBS-treated

0

–

97

↑ 97 (6.6)

0

–

7

↑ 7 (7.1)

–

–

–

–

Liver

PGN-treated vs. PBS-treated

14

↑ 14 (18.6)

123

↑ 109 (11.0)

32

↑ 27 (14.4)

80

↑ 72 (9.8)

 

–

↓ 14 (−6.7)

↓ 5 (−4.8)

↓ 8 (−11.8)

 

Poly I:C-treated vs. PBS-treated

1

↑ 1 (7.3)

25

↑ 24 (9.8)

0

–

36

↑ 36 (7.6)

 

–

↓ 1 (−3.8)

–

–

  1. PBS phosphate-buffered saline, PGN peptidoglycan, Poly I:C polyinosinic-polycytidylic acid. W, non-transgenic (wild-type) coho salmon on a full satiation ration, TF GH transgenic coho salmon on a full satiation ration, TR GH transgenic coho salmon on restricted ration equal to that consumed by W, D domesticated coho salmon on a full satiation ration