Proximal femoral head transcriptome reveals novel candidate genes related to epiphysiolysis in broiler chickens

BMC Genomics

Table 1 Top 10 down and upregulated genes in the proximal femur transcriptome of FHS-affected compared to healthy broilers, according to the LogFC and FDR

Ensembl ID	LogFC	FDR	Gene
ENSGALG00000027184	−5.38	5.00E-10	OLFML1
ENSGALG00000032856	−4.92	1.07E-06	GFRA2
ENSGALG00000039376	−4.88	7.40E-07	DPT
ENSGALG00000024428	−4.84	2.39E-06	C17orf67
ENSGALG00000028459	−4.46	1.18E-07	FAM180A
ENSGALG00000015307	−4.40	2.19E-07	ABI3BP
ENSGALG00000017191	−3.81	2.35E-04	ANGPTL5
ENSGALG00000043703	−3.47	1.26E-07
ENSGALG00000032220	−3.27	8.77E-07	ELN^a
ENSGALG00000016511	−3.14	7.71E-03	ADGRG2
ENSGALG00000009479	2.20	8.76E-03	SAMD9L
ENSGALG00000044811	2.21	3.60E-05	MSMB-like^a
ENSGALG00000046192	2.21	5.45E-04	CCL19^a
ENSGALG00000026727	2.25	0.0295	SLC30A10
ENSGALG00000043860	2.42	0.0030	PGR2^a
ENSGALG00000023933	2.42	0.024	G0S2
ENSGALG00000043254	2.56	1.11E-03	EPX^a
ENSGALG00000028256	2.67	3.58E-03	CCL19
ENSGALG00000023622	3.02	7.06E-03	AVD
ENSGALG00000032614	3.37	1.51E-04	CHAT2

OLFML1 Olfactomedin like 1, GFRA2 GDNF family receptor alpha 2, DPT Dermatopontin, C17orf67 Chromosome 17 open reading frame 67 orf67, FAM180A Family with sequence similarity 180 member A, ABI3BP ABI family member 3 binding protein, ANGPTL5 Angiopoietin like 5, ADGRG2 Adhesion G protein-coupled receptor G2, SAMD9L Sterile alpha motif domain containing 9-like, SLC30A10 Solute carrier family 30 member, G0S2G0/G1 switch 2, CCL19:CC:motif chemokine ligand 19, AVD Avidin, CHAT2 ADP-ribosyltransferase. ^aGenes annotated in the Ensembl 98 release. ELN: Elastin, MSMB-like: Microseminoprotein Beta Like, CCL19 C-C Motif Chemokine Ligand 19, PGR2 Progesterone receptor 2, EPX Eosinophil Peroxidase

ISSN: 1471-2164