From: Genetic dissection of canine hip dysplasia phenotypes and osteoarthritis reveals three novel loci
Trait | Chr | Locus | Alleles | N per SNP | SNP(s) | P-value from FASTA, corrected with the inflation factor lambda (λ = 1.010–1.024) |
---|---|---|---|---|---|---|
1st case-control analysis (normal hips or mild-to-severe CHD; FCI scores) | 1 | 45,382,633 45,161,186 46,279,297 46,268,586 | C/A G/C A/G C/A | 693 693 689 692 | BICF2P468585 BICF2S23248027 BICF2P357728 BICF2P1037296 | 7.03 × 10–7 1.30 × 10–6 2.52 × 10–6 9.51 × 10–6 |
2nd case-control analysis (normal hips or moderate-to-severe CHD; FCI scores) | 9 | 36,837,067 36,886,621 | G/A A/G | 520 517 | BICF2G630837405 TIGRP2P126345 | 4.96 × 10–6 7.75 × 10–6 |
3rd case-control analysis (mild CHD or moderate-to-severe CHD; FCI scores) | 9 | 36,837,067 36,886,621 | G/A A/G | 340 338 | BICF2G630837405 TIGRP2P126345 | 4.12 × 10–6 7.48 × 10–6 |