Table 3 Genes differentially spliced in response to acute Cu exposure from the global analysis combining all 6 controls with all 15 Cu exposed samples. Δψ is the absolute value of the difference in exon/intron inclusion levels between controls and Cu exposed samples
Gene ID | Description | GO Term | AS type | Spliced region | |Δψ| |
|---|---|---|---|---|---|
gene15738 | coatomer subunit gamma | binding | A3SS | Exon 3 | 0.255 |
gene7414 | lethal malignant brain tumor-like protein 3 isoform ×2 | transcription regulation; zinc ion binding | A3SS | Exon 7 | 0.342 |
gene16738 | sialin isoform ×2 | transmembrane transport | A3SS | Exon 8 | 0.291 |
gene4489 | sprouty- evh1 domain-containing protein partial | signal transduction | A3SS | Exon 4 | 0.293 |
gene8923 | hypothetical protein DAPPUDRAFT_267459 | metabolism | A3SS | Exon 3 | 0.281 |
gene7598 | hypothetical protein DAPPUDRAFT_309480 | single-stranded DNA binding | A5SS | Exon 1 | 0.302 |
gene9075 | nucleoside diphosphate kinase 7 | metabolism | A5SS | Exon 1 | 0.211 |
gene9075 | nucleoside diphosphate kinase 7 | metabolism | ES | Exon 1 partial | 0.244 |
gene11416 | protein grainyhead isoform ×1 | NA | A5SS | Exon 12 | 0.346 |
gene5664 | type i procollagen alpha 1 chain | NA | A5SS | Exon 4 | 0.202 |
gene1314 | glutathione s-transferase | protein binding | MXE | Exon 4 and 9; Exon 5 and 10 | 0.267 |
gene8790 | i’m not dead yet | transmembrane transport | MXE | Exon 11 and 12 | 0.301 |
gene8790 | i’m not dead yet | transmembrane transport | ES | Exon 12 | 0.324 |
gene14576 | pyruvate kinase-like isoform x | ion binding; metabolism | ES | Exon 9 | 0.204 |
gene7153 | tgf-beta-activated kinase 1 and map 3 k7-binding protein 2 | zinc ion binding | ES | 5′ UTR | 0.278 |
gene377 | alpha-aspartyl dipeptidase | serine-type peptidase activity; proteolysis | ES | Exon 2 | 0.231 |
gene10569 | endophilin-a isoform ×1 | protein binding; endocytosis | ES | Exon 8 | 0.213 |
gene15982 | transmembrane protein 189 | protein ubiquitination | IR | Intron 3 | 0.286 |