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Fig. 5 | BMC Genomics

Fig. 5

From: Dual indexed library design enables compatibility of in-Drop single-cell RNA-sequencing with exAMP chemistry sequencing platforms

Fig. 5

Comparison of cell types identified between inDrop V2 libraries on NextSeq and TruDrop on NovaSeq. a and c Combined t-SNE analysis of cells identified from a TruDrop and V2 library prepared from the same samples of (a) mouse and (c) human tumors. b and d sc-UniFrac tree representations of subpopulation structures for libraries presented in a and c, respectively. Cell groups enriched using V2 NextSeq libraries have red branches, while those enriched using TruDrop NovaSeq have blue branches. Thickness of branches represent level of enrichment. Distance values range from 0 to 1, with 0 representing complete overlap between two datasets

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