Fig. 1
From: Structural variation of the malaria-associated human glycophorin A-B-E region
Structure of the glycophorin reference allele. A representation of the reference allele assembled in the GRCh37/hg19 assembly is shown, with the three distinct paralogous ~ 120 kb repeats of the glycophorin region coloured green, orange and purple, carrying GYPE, GYPB and GYPA respectively. Numbers over the start and end of each paralogue represent coordinates in chromosome 4 GRCh37/hg19 assembly. Coloured bars represent fosmids used as probes in fibre-FISH, with the fosmid identification number underneath. The lower black panel is an example fibre FISH image of this reference haplotype (from sample HG02585). The fibre-FISH image is scaled approximately to match the reference above it, with approximate boundaries between glycophorin repeats shown as dashed lines