Fig. 5
From: mitch: multi-contrast pathway enrichment for multi-omics and single-cell profiling data
Comparison of gene set enrichment enrichment results downstream of different DE tools on the same RNA-seq dataset. a UpSet plot of gene sets produced by different DE tools FDR < 0.05, as calculated by unidimensional mitch. b Pairs plot of mitch s values for each gene set as processed by different DE tools. Upper triangle shows Pearson’s r. c A heatmap of 10 gene sets with the highest SD of s values across different DE tools, scaled by row. d Heatmap of individual gene members of the peptide chain elongation gene set, scaled by row. e Violin plot of enrichments of the peptide chain elongation gene set. f Observed nominal ANOVA p-value of the peptide chain elongation gene set after analysis with different DE tools