Comparative analysis of single-cell transcriptomics in human and zebrafish oocytes

BMC Genomics

Table 1 Top 25 genes that are orthologous between human and zebrafish and expressed in the top 30% of all three data sets. Average TPM was calculated using all nine samples. For a gene family, e.g., “ribosomal proteins,” only the top representative is listed. The complete list of genes can be found in Supplementary file 3

Rank	GeneID (ENSG00000+)	Symbol	Description	Average TPM
1	198712	MT-CO2	Mitochondrially encoded cytochrome c oxidase	16,481
3	198886	MT-ND4	Mitochondrially encoded NADH	9839
7	198899	MT-ATP6	mitochondrially encoded ATP synthase	8180
9	130816	DNMT1	DNA methyltransferase 1	5089
10	132646	PCNA	Proliferating cell nuclear antigen	4380
11	173207	CKS1B	CDC28 protein kinase regulatory subunit	4273
13	138326	RPS24	Ribosomal protein	2701
15	182004	SNRPE	Small nuclear ribonucleoprotein polypeptide E	2497
19	137707	BTG4	BTG anti-proliferation factor 4	1994
21	120533	ENY2	Transcription and export complex 2 subunit	1796
23	113387	SUB1	SUB1 homolog, transcriptional regulator	1663
24	113558	SKP1	S-phase kinase associated protein 1	1656
25	170315	UBB	Ubiquitin B	1611
27	132341	RAN	Member RAS oncogene family	1572
31	122674	CCZ1	Vacuolar protein trafficking and biogenesis	1526
33	198668	CALM	Calmodulin	1464
36	134057	CCNB1	Cyclin B1	1384
37	132780	NASP	Nuclear autoantigenic sperm protein	1379
39	173812	EIF1	Eukaryotic translation initiation factor 1	1285
40	221983	UBA52	Ubiquitin A⁻⁵² residue ribosomal protein fusion product 1	1183
43	076043	REXO2	RNA exonuclease 2	1056
46	115540	MOB4	MOB family member 4, phocein	1007
49	182117	NOP10	NOP10 ribonucleoprotein	962
56	214102	WEE2	WEE1 homolog 2	809
58	162961	DPY30	Histone methyltransferase complex regulatory subunit	790

ISSN: 1471-2164