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Fig. 3 | BMC Genomics

Fig. 3

From: Identification and distribution of gene clusters required for synthesis of sphingolipid metabolism inhibitors in diverse species of the filamentous fungus Fusarium

Fig. 3

Organization of genes in the fumonisin biosynthetic gene cluster and five putative novel SAM biosynthetic gene clusters (clusters SAM1 – SAM5) identified in Fusarium genomes. Yellow arrows indicate the PKS, AT and SDR genes in each cluster, while the blue arrows indicate other genes in the clusters. The arrows point in the direction of transcription. For the fumonisin cluster, numbers in arrows correspond to the FUM gene number (e.g., 21 indicates gene FUM21). For the SAM1 – SAM5 clusters, the letters within blue arrows indicate the predicted functions of the genes, based on sequence homology of predicted proteins: TF, transcription factor; DOX, dioxygenase; MFS, major facilitator superfamily transporter; P450, cytochrome P450 monooxygenase; MSDR, mannitol 2-dehydrogenase; HPH, hypothetical protein (no function predicted); MOX, FAD-binding monooxygenase; ANK, ankyrin protein; ABC, ABC transporter; NRPS, nonribosomal peptide synthetase; CARS, carnosine synthase 1; UBQL, ubiquitin ligase; DNAB, acetate regulatory DNA-binding protein; PSP1, parasitic phase-specific protein

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BMC Genomics

ISSN: 1471-2164

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