Fig. 3

Gene examples in the gene co-expression modules associated with post-partum ketosis and blood biochemical indicators. a Scatter plots reflect the correlations between expression levels (log₂TPM) of genes and levels of blood bio-indicators across 24 blood samples. C14H8orf82, ACSS1, EPB2 and PLK1 belong to Midnightblue, Darkorange, Steelblue and Lightcyan modules, respectively. b Boxplots show gene expression levels of four genes among four different physiological stages (Healthy Post-partum, H_Post; Healthy Pre-partum, H_Pre; Ketosis Post-partum, K_Post; Ketosis Pre-partum, K_Pre). The significance level (P) is determined by t-test. The “**”, “*” and “.” represent P less than 0.01, 0.05 and 0.1, respectively. c Protein-protein interaction network analysis (STRING v11 database) for genes in Steelblue (left) and Lightcyan (right) modules