Table 2 The shared pathways enriched by DEGs among all 3 comparison groups (LPS vs PBS, PGN vs PBS and poly(I:C) vs PBS)
Pathway ID | Pathway | P value | Class |
|---|---|---|---|
Shared by LPS, PGN, and poly(I:C) group | |||
 map 04611 | Platelet activation | 0.032959505 | Organismal Systems; Immune system |
 map 04510 | Focal adhesion | 0.000108165 | Cellular Processes |
Shared by LPS and PGN group | |||
 map 03030 | DNA replication | 1.47E-10 | Genetic Information Processing; Replication and repair |
 map 04110 | Cell cycle | 2.54E-09 | Cellular Processes; Cell growth and death |
 map 04113 | Meiosis - yeast | 1.67E-08 | NO ENTRY FOUND. |
 map 04115 | p53 signaling pathway | 8.51E-07 | Cellular Processes; Cell growth and death |
 map 03460 | Fanconi anemia pathway | 5.38E-06 | Genetic Information Processing; Replication and repair |
 map 04971 | Gastric acid secretion | 8.67E-05 | Organismal Systems; Digestive system |
 map 04921 | Oxytocin signaling pathway | 0.000627827 | Organismal Systems; Endocrine system |
 map 04022 | cGMP-PKG signaling pathway | 0.000631031 | Environmental Information Processing; Signal transduction |
 map 04270 | Vascular smooth muscle contraction | 0.002126258 | Organismal Systems; Circulatory system |
 map 03410 | Base excision repair | 0.02148101 | Genetic Information Processing; Replication and repair |
 map 04020 | Calcium signaling pathway | 0.032327041 | Environmental Information Processing; Signal transduction |
 map 05166 | HTLV-I infection | 0.043004689 | NO ENTRY FOUND. |
 map 00230 | Purine metabolism | 0.049496555 | Metabolism; Nucleotide metabolism |
Shared by LPS and poly(I:C) group | |||
 map 04145 | Phagosome | 0.014509814 | Cellular Processes; Transport and catabolism |
Shared by PGN and poly(I:C) group | |||
 map 05133 | Pertussis | 5.32E-05 | Human Diseases; Infectious disease: bacterial |
 map 04974 | Protein digestion and absorption | 0.003941603 | Organismal Systems; Digestive system |
 map 04512 | ECM-receptor interaction | 0.001614027 | Environmental Information Processing; Signaling molecules and interaction |
 map 04610 | Complement and coagulation cascades | 0.000712509 | Organismal Systems; Immune system |
 map 05130 | Pathogenic Escherichia coli infection | 0.013636368 | Human Diseases; Infectious disease: bacterial |
 map 05322 | Systemic lupus erythematosus | 0.011539281 | Human Diseases; Immune disease |