Skip to main content

Table 2 The shared pathways enriched by DEGs among all 3 comparison groups (LPS vs PBS, PGN vs PBS and poly(I:C) vs PBS)

From: New insights into the Manila clam and PAMPs interaction based on RNA-seq analysis of clam through in vitro challenges with LPS, PGN, and poly(I:C)

Pathway ID Pathway P value Class
Shared by LPS, PGN, and poly(I:C) group
 map 04611 Platelet activation 0.032959505 Organismal Systems; Immune system
 map 04510 Focal adhesion 0.000108165 Cellular Processes
Shared by LPS and PGN group
 map 03030 DNA replication 1.47E-10 Genetic Information Processing; Replication and repair
 map 04110 Cell cycle 2.54E-09 Cellular Processes; Cell growth and death
 map 04113 Meiosis - yeast 1.67E-08 NO ENTRY FOUND.
 map 04115 p53 signaling pathway 8.51E-07 Cellular Processes; Cell growth and death
 map 03460 Fanconi anemia pathway 5.38E-06 Genetic Information Processing; Replication and repair
 map 04971 Gastric acid secretion 8.67E-05 Organismal Systems; Digestive system
 map 04921 Oxytocin signaling pathway 0.000627827 Organismal Systems; Endocrine system
 map 04022 cGMP-PKG signaling pathway 0.000631031 Environmental Information Processing; Signal transduction
 map 04270 Vascular smooth muscle contraction 0.002126258 Organismal Systems; Circulatory system
 map 03410 Base excision repair 0.02148101 Genetic Information Processing; Replication and repair
 map 04020 Calcium signaling pathway 0.032327041 Environmental Information Processing; Signal transduction
 map 05166 HTLV-I infection 0.043004689 NO ENTRY FOUND.
 map 00230 Purine metabolism 0.049496555 Metabolism; Nucleotide metabolism
Shared by LPS and poly(I:C) group
 map 04145 Phagosome 0.014509814 Cellular Processes; Transport and catabolism
Shared by PGN and poly(I:C) group
 map 05133 Pertussis 5.32E-05 Human Diseases; Infectious disease: bacterial
 map 04974 Protein digestion and absorption 0.003941603 Organismal Systems; Digestive system
 map 04512 ECM-receptor interaction 0.001614027 Environmental Information Processing; Signaling molecules and interaction
 map 04610 Complement and coagulation cascades 0.000712509 Organismal Systems; Immune system
 map 05130 Pathogenic Escherichia coli infection 0.013636368 Human Diseases; Infectious disease: bacterial
 map 05322 Systemic lupus erythematosus 0.011539281 Human Diseases; Immune disease