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Table 4 List of prioritized genes

From: Deciphering the mode of action and position of genetic variants impacting on egg number in broiler breeders

Rank

Gene ID

Description

GGA

Overall

p-value

1

GDF15

growth differentiation factor 15

28

0.019

2

BHLHE40

basic helix-loop-helix family member e40

12

0.027

3

JUND

JunD proto-oncogene, AP-1 transcription factor subunit

28

0.029

4

GDF3

growth differentiation factor 3

28

0.030

5

COMP

cartilage oligomeric matrix protein

28

0.037

6

ITPR1

inositol 1,4,5-trisphosphate receptor type 1

12

0.039

7

ELF3

E74 like ETS transcription factor 3

26

0.040

8

ELL

elongation factor for RNA polymerase II

28

0.044

9

CRLF1

cytokine receptor like factor 1

28

0.047

10

IFI30

IFI30, lysosomal thiol reductase

28

0.048

11

ISYNA1

inositol-3-phosphate synthase 1

28

0.050

12

RAB3A

RAB3A, member RAS oncogene family

28

0.051

13

CRTC1

CREB regulated transcription coactivator 1

28

0.057

14

GPR37L1

G protein-coupled receptor 37 like 1

26

0.057

15

PIK3R2

phosphoinositide-3-kinase regulatory subunit 2

28

0.060

16

GFRA2

GDNF family receptor alpha 2

22

0.061

17

EDEM1

ER degradation enhancing alpha-mannosidase like protein 1

12

0.069

18

FKBP8

FK506 binding protein 8

28

0.069

19

PDE4C

phosphodiesterase 4C

28

0.083

20

LGR6

leucine rich repeat containing G protein-coupled receptor 6

26

0.086

21

HOMER3

homer scaffolding protein 3

28

0.112

22

LSM4

LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated

28

0.114

23

COPE

coatomer protein complex subunit epsilon

28

0.149

24

ARL8B

ADP ribosylation factor like GTPase 8B

12

0.150

25

PTPN7

protein tyrosine phosphatase, non-receptor type 7

26

0.152

26

PGPEP1

pyroglutamyl-peptidase I

28

0.156

27

C19orf60 (also known as REX1BD)

chromosome 19 open reading frame 60

28

0.172

28

SSBP4

single stranded DNA binding protein 4

28

0.192

29

UBA52

ubiquitin A-52 residue ribosomal protein fusion product 1

28

0.192

30

UPF1

UPF1, RNA helicase and ATPase

28

0.192

31

CERS1

ceramide synthase 1

28

0.198

32

MPV17L2

MPV17 mitochondrial inner membrane protein like 2

28

0.228

33

DOK2

docking protein 2

22

0.262

34

XPO7

exportin 7

22

0.292

35

ARL8A

ADP ribosylation factor like GTPase 8A

26

0.340

36

DDX49

DEAD-box helicase 49

28

0.345

37

SUGP2

SURP and G-patch domain containing 2

28

0.345

38

KLHL26

kelch like family member 26

28

0.345

39

KIF21B

kinesin family member 21B

26

0.351

40

KXD1

KxDL motif containing 1

28

0.351

41

LRRC25

leucine rich repeat containing 25

28

0.588

42

TMEM59L

transmembrane protein 59 like

28

0.588

43

PTPRVP

protein tyrosine phosphatase, receptor type, V, pseudogene

26

1.000