Table 2 Association between five coding variants and different traits. The five variants have been previously associated with specific phenotypes (coat colour or recessive genetic defects) and the corresponding gene names are indicated in the table. The associations are reported in terms of p-values and posterior inclusion probability (PIP) estimated with the Bayesian Sparse Linear Mixed Model
Gene | RNF11 [29] | KITLG [37] | WWP1 [35] | MRC2 [28] | ATAP2A1 [36] | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Dwarfism | Roan coat colour | Fitness | Crooked-tail syndrome | Congenital Muscular dystonia 1 | |||||
Trait | PIP | p-value | PIP | p-value | PIP | p-value | PIP | p-value | PIP | p-value |
Shoulder muscling | 0.01 | 9.6e-5 | 0 | 0.78 | 1 | 1.4e-11 | 0.02 | 1.0e-4 | 0 | 0.39 |
Top muscling | 0.92 | 3.8e-11 | 0 | 0.25 | 1 | 1.2e-12 | 0.91 | 2.4e-6 | 0 | 0.34 |
Skin thickness | 0 | 0.16 | 1 | 5.4e-12 | 0 | 2.1e-1 | 0 | 0.57 | 0 | 0.09 |
Height | 0.28 | 4.2e-8 | 0 | 0.74 | 1 | 1.6e-11 | 0.68 | 1.2e-12 | 0.01 | 0.42 |
Muscular development | 0.37 | 4.1e-9 | 0 | 0.34 | 1 | 2.3e-12 | 0.81 | 5.0e-8 | 0 | 0.13 |
Rump | 0 | 1.7e-2 | 0 | 0.50 | 0 | 6.7e-2 | 0.97 | 1.6e-13 | 1 | 2.0e-8 |
Length | 0.62 | 3.5e-7 | 0 | 0.59 | 1 | 7.2e-11 | 0.75 | 1.5e-8 | 0 | 0.76 |
Chest width | 0.01 | 6.5e-3 | 0 | 0.45 | 0.76 | 7.4e-6 | 0.03 | 3.8e-5 | 0 | 0.39 |
Pelvis width | 0 | 5.7e-2 | 0 | 0.56 | 0.91 | 5.3e-5 | 0.03 | 3.2e-5 | 0 | 0.46 |
Rib shape | 0 | 4.0e-4 | 0 | 0.31 | 0 | 3.4e-2 | 1 | 2.0e-10 | 0 | 0.94 |
Pelvis length | 0.03 | 2.5e-3 | 0 | 0.24 | 0.99 | 5.8e-8 | 0.42 | 2.6e-9 | 0 | 0.23 |
Tail set | 0 | 1.0e-2 | 0 | 0.15 | 0.01 | 4.8e-2 | 0 | 0.98 | 0 | 0.01 |
Buttock muscling (side) | 0.02 | 6.7e-6 | 0 | 0.60 | 0.23 | 2.9e-3 | 0.01 | 3.1e-3 | 0.29 | 7.6e-5 |
Buttock muscling (rear) | 0.01 | 4.3e-4 | 0 | 0.10 | 1 | 2.8e-11 | 0.54 | 8.0e-8 | 0 | 0.34 |