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Table 3 Values of the parameters needed to determine the infinitesimal generator (Q) using 4 normal cell lines, where \(d_{i} = 1- \sum _{j=1}^{N} \left (p_{{ij}}^{+} + p_{{ij}}^{-}\right)\)

From: Analysis of two mechanisms of telomere maintenance based on the theory of g-Networks and stochastic automata networks

  Translation (\(\lambda _{i}^{+}\)) Degradation (\(\lambda _{i}^{-}\)) μi di  
CEBPA 4 1.18489 3 0.333  
E2F1 4 1.79118 3 0.333  
FOXM1 4 2.78510 2 0.5  
c-MYC 5 6.70809 3 0.333  
hTERT 5 6.07682 1 1  
Normal: Activation/transcription processes (\(p_{{ij}}^{+}\))
  CEBPA E2F1 FOXM1 c-MYC hTERT
CEBPA 0 0 0 0 0
E2F1 0 0 0 0.333 0
FOXM1 0 0 0 0.5 0
c-MYC 0 0 0 0 0.333
hTERT 0 0 0 0 0
Normal: Repression process (\(p_{{ij}}^{-}\))
  CEBPA E2F1 FOXM1 c-MYC hTERT
CEBPA 0 0.333 0.333 0 0
E2F1 0 0 0 0 0.333
FOXM1 0 0 0 0 0
c-MYC 0.333 0 0 0 0
hTERT 0 0 0 0 0
  1. The “service” (or firing) rate of gene i, denoted by μi, represents the protein–protein interactions, e.g., phosphorylation and ubiquitination. Gene i activates and inhibits gene j with probability \(p_{{ij}}^{+}\) and \(p_{{ij}}^{-}\), respectively. Genes in the rows correspond to the “starting” genes, while those in columns to the ending genes