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Table 4 Values of the parameters that are needed to determine the infinitesimal generator (Q) using 18 ALT cell lines

From: Analysis of two mechanisms of telomere maintenance based on the theory of g-Networks and stochastic automata networks

 

Translation (\(\lambda _{i}^{+}\))

Degradation (\(\lambda _{i}^{-}\))

μi

di

 

CEBPA

4

1.18489

3

0.5433

 

E2F1

4

1.79118

3

0.1258

 

FOXM1

4

2.78510

2

0.2417

 

c-MYC

5

6.70809

3

0.0280

 

hTERT

5

6.07682

1

1

 

ALT: Activation/transcription processes (\(p_{{ij}}^{+}\))

 

CEBPA

E2F1

FOXM1

c-MYC

hTERT

CEBPA

0

0

0

0

0

E2F1

0

0

0

0.5574

0

FOXM1

0

0

0

0.7583

0

c-MYC

0

0

0

0

0.3855

hTERT

0

0

0

0

0

ALT: Repression process (\(p_{{ij}}^{-}\))

 

CEBPA

E2F1

FOXM1

c-MYC

hTERT

CEBPA

0

0.2268

0.2230

0

0

E2F1

0

0

0

0

0.3168

FOXM1

0

0

0

0

0

c-MYC

0.5865

0

0

0

0

hTERT

0

0

0

0

0

  1. The definitions and representations of \(d_{i}, \mu _{i}, p_{{ij}}^{+}\) and \(p_{{ij}}^{-}\) are the same as in Table 3