Fig. 1From: Chronological set of E. coli O157:H7 bovine strains establishes a role for repeat sequences and mobile genetic elements in genome diversificationComparison of FRIK804 and Sakai chromosomes. Alignment of the FRIK804 (outer) and Sakai (inner) chromosome found disruption of synteny by large-scale structural alterations. To evaluate each dissimilarity, the locations of relevant genomic features (prophage, PLE, IS, rRNA and tRNA) were identified. Non-conserved regions (e.g. indel-1 and indel-2) of each chromosome are shaded lighter relative to conserved regions. Evidence of mosaicism in otherwise conserved prophage was evident in several pairs of homologs, including the stx2-prophage. The majority of dissimilarities that distinguished each chromosome were associated with MGE. A 1.15 Mb inversion is denoted by the offset region in FRIK804. Indel-1 was classified as a PLE and indel-2 was not associated with any MGE. Mu-like prophage were integrated at different loci. The locations of rRNA and tRNA regions are denoted by dark green and light green regions, respectivelyBack to article page