Fig. 3
From: Relatively semi-conservative replication and a folded slippage model for short tandem repeats
The DNA chain is highly curved or folded in the nucleus and the impossible curved slippage model. a Schematic diagram of the size of the nuclear space (top) [61]; The normal replicating enzymes complex straighten the DNA chain, while the disturbed replicating enzymes complex may cause the DNA molecule return to curved state (bottom). b Impossible curved template slippage model according to the strict geometric calculation of the space of a nucleotide and the stability of hydrogen and phosphodiester bonds (top); Mono- and dinucleotide repeats may be impossibly produced in curved replicating strands (middle and bottom)