Table 3 Top 5 GO annotations of the three categories (BP: Biological Process, CC: Cellular Components, MF: Molecular Function) significantly enriched by differentially expressed genes
| Â | GO ID | Term | Annotated | Significant | Expected | P-value |
|---|---|---|---|---|---|---|
CS vs LS | ||||||
 BP | GO:0055114 | oxidation-reduction process | 413 | 4 | 1.73 | 0.00017 |
 BP | GO:0006821 | chloride transport | 14 | 4 | 0.06 | 0.00047 |
 BP | GO:0007155 | cell adhesion | 75 | 1 | 0.31 | 0.00089 |
 BP | GO:0035295 | tube development | 10 | 1 | 0.04 | 0.00584 |
 BP | GO:0034220 | ion transmembrane transport | 250 | 2 | 1.05 | 0.00624 |
 CC | GO:0016021 | integral component of membrane | 1230 | 9 | 4.39 | 4.2E-06 |
 CC | GO:0016020 | membrane | 2483 | 11 | 8.87 | 0.0043 |
 CC | GO:0005615 | extracellular space | 51 | 1 | 0.18 | 0.0125 |
 CC | GO:0005886 | plasma membrane | 325 | 3 | 1.16 | 0.0304 |
 CC | GO:0030054 | cell junction | 66 | 2 | 0.24 | 0.033 |
 MF | GO:0046872 | metal ion binding | 1001 | 4 | 4.91 | 0.00079 |
 MF | GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 70 | 1 | 0.34 | 0.00107 |
 MF | GO:0005506 | iron ion binding | 50 | 1 | 0.25 | 0.00128 |
 MF | GO:0005247 | voltage-gated chloride channel activity | 4 | 2 | 0.02 | 0.00165 |
 MF | GO:0004175 | endopeptidase activity | 188 | 1 | 0.92 | 0.00337 |
CS vs HS | ||||||
 BP | GO:0051276 | chromosome organization | 156 | 1 | 0.05 | 0.02219 |
 BP | GO:0006996 | organelle organization | 427 | 1 | 0.15 | 0.48991 |
 BP | GO:0006793 | phosphorus metabolic process | 815 | 1 | 0.28 | 0.76061 |
 BP | GO:0009987 | cellular process | 4286 | 2 | 1.49 | 0.8504 |
 BP | GO:0006796 | phosphate-containing compound metabolic process | 799 | 1 | 0.28 | 0.85274 |
 CC | GO:0016021 | integral component of membrane | 1230 | 1 | 0.52 | 0.000016 |
 CC | GO:0016020 | membrane | 2483 | 1 | 1.04 | 0.0039 |
 CC | GO:0031224 | intrinsic component of membrane | 1235 | 1 | 0.52 | 0.1317 |
 CC | GO:0044464 | cell part | 2983 | 1 | 1.25 | 0.7094 |
 CC | GO:0005623 | cell | 3005 | 1 | 1.26 | 0.7295 |
 MF | GO:0046872 | metal ion binding | 1001 | 1 | 0.45 | 0.00059 |
 MF | GO:0043169 | cation binding | 1018 | 1 | 0.45 | 0.47576 |
 MF | GO:0004659 | prenyltransferase activity | 10 | 1 | 0 | 0.49112 |
 MF | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups | 27 | 1 | 0.01 | 0.58447 |
 MF | GO:0005488 | binding | 3747 | 2 | 1.67 | 0.69304 |