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Fig. 1 | BMC Genomics

Fig. 1

From: Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines

Fig. 1

Venn diagrams of overlap between endogenous, statin-treated, and average eQTLs from the meta-analysis and ancestry subsets. Overlap of (a) endogenous (b) statin-treated and (c) average eQTL eGenes between European and African American ancestry subsets and the meta-analysis. The majority of eQTLs identified are not ancestry specific, and the numbers of eGenes identified increases with sample size. d Overlap of eGenes from endogenous, statin-treated, and average eQTL meta-analyses. Statin treatment did not significantly change numbers of eGenes, but averaging endogenous and statin-treated expression levels offered increased power for eQTL analysis. Overlap of European and African American ancestry endogenous eQTLs with (e) statin-treated and (f) average eQTLs. Venn diagrams were created in Venny 2.1 [24]

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