Fig. 1

ASH1L protein conservation. a Schematic representation of a protein alignment between Mus, rat, BW, PO, cow, human, and dog ASH1L proteins. Numbers across the top represent approximate amino acid locations. Block arrows represent conserved protein domains. Conservation graph at the bottom indicates amino acid percent conservation between the seven species. Asterisks indicate approximate locations for amino acid differences between BW and PO. b Regional protein alignment for ASH1L in areas surrounding an amino acid difference between BW and PO, with amino acid locations indicated across the top