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Fig. 1 | BMC Genomics

Fig. 1

From: First insight into the whole-genome sequence variations in Mycobacterium bovis BCG-1 (Russia) vaccine seed lots and their progeny clinical isolates from children with BCG-induced adverse events

Fig. 1

Schematic view of relationships between vaccine strain BCG-1 (Russia) parent seed lots, commercial vaccine lots, and their progeny clinical strains. Rectangle boxes correspond to the original seed lots with dates of lyophilization shown in parentheses. Rectangle shadowed boxes depict the sequenced seed lots (dates of lyophilization shown in parentheses). Dashed circles show commercial vaccine lots (were not available for sequencing) used for immunization with dates of inoculation in parentheses. Square boxes mark sequenced BCG clinical isolates (dates of BCG culture isolation shown in parentheses). Gray-scale small boxes depict sequence variants in genes related to particular proteins (proportions shown in parentheses) in seed lots 361, 367, 368, and their progeny clinical isolates. See Table 1 for more details

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BMC Genomics

ISSN: 1471-2164

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