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Table 1 Genes with a role in survival during starvation as determined by Tn-seq. Genes of which the transposon mutants were reduced by more than − 10-fold upon incubation in PBS for 7 days, using a BH-adjusted P-value of < 0.05 as cut-off for statistical significance

From: Conditionally essential genes for survival during starvation in Enterococcus faecium E745

Locus Tag Name Function Fold Change P-value (BH adjusted)
EfmE745_02439 usp Putative universal stress protein <−2.5 × 105 0.023
EfmE745_02361 entA Bacteriocin EntA <−9.2 × 104 0.020
EfmE745_02364 exuR DNA-binding transcriptional repressor −1.9 × 103 0.034
EfmE745_01205 lacD2 Tagatose 1,6-diphosphate aldolase 2 −1.6 × 103 0.018
EfmE745_02646 sacY Levansucrase and sucrase synthesis operon antiterminator − 922.6 0.020
EfmE745_00210 hypothetical protein − 639.1 0.042
EfmE745_00142 DNA alkylation repair enzyme − 548.8 0.034
EfmE745_00731 licA_1 Lichenan-specific phosphotransferase enzyme IIA component − 396.6 0.039
EfmE745_02217 gbpA GlcNAc-binding protein A precursor −280.7 0.043
EfmE745_00135 Mga helix-turn-helix domain protein −44.8 0.034
EfmE745_03020 hypothetical protein −43.1 0.010
EfmE745_00219 rhaD Rhamnulose-1-phosphate aldolase −33.3 0.028
EfmE745_02998 hypothetical protein −33.1 0.010
EfmE745_00220 rhaM L-rhamnose mutarotase −26.4 0.034
EfmE745_02641 putative HTH-type transcriptional regulator −23.1 0.034
EfmE745_01197 hypothetical protein −22.1 0.023
EfmE745_01055 ABC-2 family transporter protein −17.8 0.040
EfmE745_01627 PTS system glucitol/sorbitol-specific transporter subunit IIA −15.9 0.016
EfmE745_00728 cshA DEAD-box ATP-dependent RNA helicase −14.1 0.038
EfmE745_00043 tmpC Membrane lipoprotein TmpC precursor −13.6 0.016
EfmE745_02660 drrA Daunorubicin/doxorubicin resistance ATP-binding protein −12.6 0.046
EfmE745_00895 rnmV Ribonuclease M5 −12.4 0.038
EfmE745_00502 metP Methionine import system permease protein −12.3 0.033
EfmE745_00095 Arsenical resistance operon trans-acting repressor ArsD −11.4 0.029