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Table 1 DGAT1 junction splicing efficiency association statistics for the top sequence variants and K232A

From: A new mechanism for a familiar mutation – bovine DGAT1 K232A modulates gene expression through multi-junction exon splice enhancement

DGAT1 Intron Top SNP P-value K232A Rank K232A P-value
Intron 1 rs209328075 3.60 × 10−30 69 6.19 × 10−29
Intron 2 K232A 5.25 × 10−46 1 5.25 × 10− 46
Intron 3 rs211223469 4.63 × 10−18 30 3.95 × 10−17
Intron 4 rs110825388 8.23 × 10−4 27 0.00119
Intron 5 rs209328075 7.47 × 10−5 61 3.17 × 10−4
Intron 6 rs377961056 2.43 × 10−4 1279 0.515
Intron 7 K232A 9.91 × 10−16 1 9.91 × 10−16
Intron 8 rs109162116 4.37 × 10−19 28 7.48 × 10−19
Intron 9 rs210757486 0.00742 1475 0.427
Intron 10 rs134628055 5.48 × 10−4 2278 0.827
Intron 11 rs109050667 8.23 × 10−10 70 1.68 × 10−8
Intron 12 rs137017663 3.26 × 10−5 377 0.0148
Intron 13 rs383740077 3.82 × 10−6 459 0.0312
Intron 14 rs443459090 4.25 × 10−7 214 1.32 × 10−4
  1. The fourth column displays the ranking of the association between K232A and splicing at the indicated intron, compared to all the markers. The significance of the K232A association is presented in the fifth column, compared to the P-value of the most-significantly associated variant in the third column (identical if the most significant variant was K232A). P-values smaller than the Bonferroni threshold (P = 1.14 × 10− 6) are highlighted using bold type