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Fig. 1 | BMC Genomics

Fig. 1

From: ClusterM: a scalable algorithm for computational prediction of conserved protein complexes across multiple protein interaction networks

Fig. 1

a Performance comparison on the yeast-human reference conserved protein complex dataset. NetworkBLAST-M failed to obtain meaningful results due to the large sizes of the PPI networks in IntActYH. b The conserved NuA4 histone acetyltransferase protein complex detected by ClusterM and AlignNemo. c The conserved multimeric ribonuclease P complex detected by ClusterM and AlignMCL. The nodes with red border edges represent the proteins that do not bear any sequence similarity between two PPI networks. Solid lines denote protein-protein interactions and gray dotted lines indicate sequence similarity

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BMC Genomics

ISSN: 1471-2164

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